Tuesday, June 27, 2017

Reducing Risk of Alzheimer’s


Researchers at Temple University recently published a study in Annals of Clinical and Translational Neurology indicating extra virgin olive oil (evoo) protects memory and reduces  classic markers of Alzheimer’s disease such as  amyloid-beta plaques and neurofibrillary tangles in the brain.

Studying the relationship of evoo on Alzheimer’s, researchers fed one group of mice a diet rich in olive oil and a second group of mice regular chow. Mice fed the evoo diet for 3 months and 6 months performed better on working memory, spatial memory, and learning abilities tests than the group fed regular chow. There was also a dramatic difference in nerve cell appearance and function of brain tissue between the two groups.

Mice fed the evoo diet had less brain  inflammation. They had better synaptic integrity, which is the connection between neurons. They also had a dramatic increase in nerve cell autophagy activation; a cellular process that clears out toxins and debris, such as amyloid plaques and neurofibrillary tangles.

Neurofibrillary tangles are believed to contribute to nerve cell dysfunction in the brain, resulting in Alzheimer’s memory problems.

Researchers concluded “Thanks to the autophagy activation, memory and synaptic integrity were preserved, and the pathological effects in animals otherwise destined to develop Alzheimer’s disease were significantly reduced.”

Researchers plan to continue their study on the same mice who have developed plaques and tangles to determine if a diet rich in evoo could stop or reverse Alzheimer’s once present. 

Olive oil has a medium-high smoking point and can withstand cooking temperatures to up 375-400F making it a good oil for salads, baking, oven cooking, and stir-frying. 1 tbs has 120 calories so watch the amount you use if you are also watching your waistline.


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